Revivogen
What is Revivogen?
Revivogen is a branded shampoo and conditioner made from natural ingredients marketed for the prevention of hair loss. Like all of the other natural products for hair loss, Revivogen is not FDA approved which means there is no firm evidence to indicate that it can prevent or reverse hair loss. Unfortunately there are no strict regulations for natural products so it is difficult to know for sure how effective a natural product is.
How does Revivogen work?
The active ingredients in Revivogen shampoo are Gamma Linolenic acid (GLA), Alpha Linolenic acid (ALA), Linoleic Acid, Oleic Acid, Azaleic Acid, Vitamin B6, Zinc, Saw Palmetto Extract, Beta-Sitosterol and Procyanidin Oligomers. Here are details of the clinical studies Revivogen refer to for these ingredients:
Gamma Linolenic acid (GLA), Alpha Linolenic acid (ALA), Linoleic Acid:
The Revivogen website states that these are ‘proven’ 5-alpha reductase inhibitors. Because 5-alpha reductase is the product that causes Testosterone to convert to Dihydrotestosterone (DHT), it makes sense that blocking this substance will inhibit the formation of DHT and therefore prevent hair loss. However, the clinical studies Revivogen refer to for these products are either carried out on mice or in cultured conditions (cell or skin samples studied in a lab). The conditions in which these studies were carried out may not have produced accurate examples of the effects the product would have if applied externally to a human being.
Azelaic Acid, Vitamin B6 and Zinc Sulphate
In a clinical study involving cultured skin samples the combination Azelaic Acid, Zinc Sulphate and Vitamin B6 applied to the skin resulted in significant inhibition of 5-alpha reductase. The study does not make clear the concentrations of each substance so it is difficult to compare the amount contained to that contained in Revivogen. This is another example of a study that does not accurately signify the conditions of the way Revivogen is used on living humans so again is difficult to judge whether the results are significant.
Saw Palmetto
Saw Palmetto can be effective in reducing 5-alpha reductase presence but studies involved cultured cells and were therefore merely a vague indication of the effects that Saw Palmetto might have in humans for the prevention of hair loss. For an effective clinical study it is important that the product is tested on living humans.
Procyanidin B-2
Revivogen talk of three studies for Procyanidin B-2 on their website. The first, unlike any of the other studies listed so far, was carried out on humans. 29 men took part in the study but there is no mention that they were experiencing hair loss. The study claims that on average, the 19 men using Procyanidin B-2 (10 used a placebo) experienced an increase in the mean diameter of their hair as well as an increase in hair count.
The study was not controlled or peer-reviewed and seemed to be carried out by the manufacturers of Revivogen so it’s difficult to say whether the results were fairly measured. The study was also carried out on a small number of subjects – too little to obtain an accurate indication of the product’s effects on hair loss.
The second and third study consisted again of either testing on live mice or cultured cells from mice so results on live humans in the dose administered within Revivogen may not resemble the results from the study.
In conclusion
Very little is known about Revivogen shampoo and conditioner, including critically, exactly how it works and how scientific studies have been conducted. We see no firm evidence that this product lives up to its claims, and possibly more important, this view seems to be shared by those who have tried using it. We do not recommend the use of any topical lotions or tablets to combat hair loss, but if you are considering trying one of these lotions, this one seems unlikely to produce the results you’re aiming for.
Tags: Hair Loss Shampoo, Revivogen
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